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WHO urges ‘immediate action’ after deaths caused by India-made cough syrups

United Nations/Geneva, January 24 (KMS): In the wake of death of children linked to cough syrups and medicines made by manufacturers based in India and Indonesia, the World Health Organization (WHO) has issued an “urgent call to action” to countries to detect and respond to incidents of falsified medical products and protect children from contaminated medicines.

The WHO said that over the past four months, countries reported several incidents of over-the-counter cough syrups for children with confirmed or suspected contamination with high levels of diethylene glycol (DEG) and ethylene glycol (EG). It said, the cases are from at least seven countries, associated with more than 300 fatalities in three of these countries, with most young children under the age of five. It said the contaminants are toxic chemicals used as industrial solvents and antifreeze agents that can be fatal even in small amounts, and should never be found in medicines.

“WHO is releasing an urgent call to action to countries to prevent, detect and respond to incidents of substandard and falsified medical products,” the global health agency said.

Since October last year, the WHO has issued three global medical alerts over substandard paediatric medicines and syrups. In October 2022, it issued an alert over Promethazine Oral Solution, Kofexmalin Baby Cough Syrup, Makoff Baby Cough Syrup and Magrip N Cold Syrup manufactured by Maiden Pharmaceuticals Limited, Haryana, India. The four “substandard products” were identified in the Gambia and reported to the WHO in September 2022.

In November, an alert was issued by the WHO over eight products, including Unibebi Cough Syrup, Unibebi Demam Paracetamol Drops and Unibebi Demam Paracetamol Syrup, identified in Indonesia and manufactured by PT Afi Farma.

Earlier this month, the WHO issued an alert to warn against the use of two “substandard” cough syrups manufactured by Marion Biotech, India that have been linked to the deaths of 18 children in Uzbekistan. Ambronol syrup and DOK-1 Max syrup were manufactured by Marion Biotech, based in Noida, Uttar Pradesh. The global health organisation issued the alert saying the syrups fail to meet quality standards and contain contaminants that can prove fatal.

The WHO’s medical product alerts were rapidly disseminated to the national health authorities of all 194 WHO Member States.

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